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Colts vs Titans Prediction & NFL Odds For Week 6

Indianapolis is favored on the road in their week six matchup against the Titans. The game, set for 1:00 ET on Sunday, October 13th at Nissan Stadium in Nashville, is being televised on CBS. The Colts’ money line odds are -115, while the Titans’ money line odds are -106. The current point spread has the Colts -1, and the over/under line is 42.5 points.

Prediction at a Glance for Titans vs Colts

  • We have the Colts winning this one by a score of 20 to 16
  • Not only do we have the Colts winning straight-up, we have them covering the spread at -1
  • We see this game finishing below the line of 42.5 points

Betting Odds & Lines for this Game

  • Spread: Colts -1 | Titans +1
  • Total: 42.5
  • MoneyLine: Colts -115 | Titans -106

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Colts vs. Titans Prediction: MoneyLine

Joe Flacco has been impressive over the last two weeks, throwing for 359 yards and 3 touchdowns in week 5 against the Jaguars, following his 168-yard, 2-touchdown performance in week 4. In week 5, he completed 33 of 44 passes and posted a passer rating of 121. Alec Pierce led the Colts in receiving with 134 yards on 3 catches, while Trey Sermon had 38 rushing yards on 10 carries.

Indianapolis is currently 16th in our offensive power rankings. They are 12th in passing yards per game (225.2) and 18th in rushing attempts, averaging 125.2 yards per game on the ground. The Colts rank 11th in 3rd-down conversions, with a 41.7% success rate, and are 24th in the league in red zone conversion percentage.

Heading into week 6, the Titans rank 30th in our offensive power rankings, averaging 19.8 points per game, which is 19th in the NFL. They are 28th in the league in yards per game (256.2) and 27th in passing yards per game (145), with 28.8 pass attempts per game. On the ground, Tennessee is 18th in rushing yards per game (111.2) on 26.2 attempts per contest. They have been strong in the red zone, converting 81.8% of their trips, ranking 4th in the NFL.

Will Levis is questionable for week 6 with a shoulder injury. In week 4, Mason Rudolph started, throwing for 85 yards on 9/17 passing. Tony Pollard led the rushing attack with 88 yards on 22 carries, and DeAndre Hopkins had 31 receiving yards on 2 catches.

  • Free MoneyLine Prediction Colts -115 (Bet Now)

Colts vs. Titans Prediction: Total

In their most recent game against the Jaguars, the Colts’ defense struggled to stop the pass, allowing 371 yards through the air on 82.4% completions. They gave up 497 total yards in the 37-34 loss, and the Jaguars took advantage of big plays in the passing game, averaging 10.9 yards per attempt.

On the ground, the Colts allowed 126 yards on just 23 attempts, giving up 5.5 yards per attempt. Indianapolis didn’t manage to sack the quarterback and lost the tackles for loss differential in this game. The Jaguars also converted 50% of their third down attempts against the Colts.

The Titans’ defense was dominant in their most recent game, allowing just 78 passing yards in a 31-12 win over the Dolphins. Miami managed just 14 completions and 184 total yards. Tennessee defended the run well, giving up only 106 yards on 30 attempts.

On third down, the Titans allowed the Dolphins to convert just 16.7% of their chances. They also had two sacks and held Miami to 63.6% completions. The Titans’ defense matched up well in the passing game, as both their passing yards allowed and their passing yards per attempt allowed were 3.5.

  • Free MoneyLine Prediction UNDER 42.5 (Bet Now)

Colts vs. Titans Prediction: Spread

Heading into week 6, the Colts have a 41.2% chance of making the playoffs and a 12.9% chance of winning the AFC South. They currently rank 22nd in our NFL power rankings. Indianapolis is 2-3 this season, with both of their wins coming at home. They are 0-2 on the road, including a 37-34 loss to the Jaguars in week 5. Despite the loss, the Colts covered the 3.5-point spread, bringing their ATS record to 4-1.

Indianapolis has covered the spread in three straight games, including two as underdogs. Their average scoring margin is -0.6 points per game. The over has hit in two straight Colts games, with an average of 48.2 points scored in their games this season.

  • Through their last three games, the Colts have a record of 2-1. Against the spread, the team is 3-0 in these same games while going 2-1 on the over/under.
  • Through their last five road contests, the Colts offense has averaged 19 points per game while allowing an average of 28. Indianapolis posted an overall record of 1-4 while going 2-3 ATS.

Heading into week 6, the Titans have a 1-3 record, putting them 3rd in the AFC South. After three straight losses to start the season, Tennessee finally got a win in week 4, beating the Dolphins 31-12 on the road. The Titans were 2.5-point underdogs in that game, but they easily covered the spread. The over (37.5) also hit, with the teams combining for 43 points.

According to our power rankings, the Titans are 25th in the NFL, and they have a 14.1% chance of making the playoffs. Their O/U record is 2-1-1, with the over hitting in two straight games. Their games are averaging 42.2 points this season, while the average O/U line has been 39.6.

  • The Titans have gone 1-2 over their last three regular season games. Across these games, their ATS record was just 1-2, while posting an over-under record of 2-0-1.
  • Through their last five home games, Tennessee has an ATS record of just 2-3. However, their overall record was 2-3 while averaging 18 points per game.
  • Free Spread Prediction Colts -1 (Bet Now)

Colts vs. Titans Pick: Colts Moneyline (-115)

For this week six matchup between the Colts and Titans, we have the Colts coming out on top by a score of 22-19. Even though the Titans are the slight favorites at +1, we are going with the Colts to not only win this game but cover the spread as road favorites.

As for the best way to bet the over/under, we like taking the under, with our projections pointing to a combined score of 41 points and the line currently sitting at 42.5 points.

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