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Colts vs Jaguars Prediction & NFL Odds For Week 5

ByUSA Wager

The Jaguars are favored at -152 on the money line as they host the Colts at 1:00 ET on Sunday, October 6th at EverBank Stadium in Jacksonville, FL. The Colts are +127 on the money line, and the Jaguars are -3 point favorites on the point spread. The over/under line is set at 46 points for this week five AFC South matchup. If you are looking to watch this one on TV, it will be on CBS.

Prediction at a Glance for Jaguars vs Colts

  • We have the Colts winning this one by a score of 25 to 20
  • Not only do we have the Colts winning straight-up, we have them covering the spread at +3
  • We see this game finishing below the line of 46 points

Betting Odds & Lines for this Game

  • Spread: Colts +3 | Jaguars -3
  • Total: 46
  • MoneyLine: Colts +127 | Jaguars -152

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Colts vs. Jaguars Prediction: MoneyLine

Indianapolis’ offense picked up 22 first downs in their 27-24 win over the Steelers, with Joe Flacco throwing for 168 yards and two touchdowns. The Colts’ running game was led by Jonathan Taylor, who rushed for 88 yards on 21 carries and found the endzone once. Flacco completed 61% of his passes and had a passer rating of 105.

Michael Pittman Jr. was the top receiver in the game, finishing with 113 yards on six catches. The Colts’ offense converted on 53.3% of their third down attempts and averaged 4.2 yards per rush on 32 attempts. Flacco was sacked twice and finished with 225 passing yards.

The Jaguars’ offense managed 17 first downs in their 24-20 loss to the Texans, piling up 158 rushing yards on 24 attempts. However, their passing game struggled, with Trevor Lawrence completing just 18 of 33 passes for 155 yards. Lawrence did throw two touchdowns and ended with an 89 passer rating.

Brian Thomas Jr. led the Jaguars with 86 yards receiving and one touchdown. Tank Bigsby was the top rusher with 90 yards on just seven carries, including a 58-yard run.

  • Free MoneyLine Prediction Colts +127 (Bet Now)

Colts vs. Jaguars Prediction: Total

In their 27-24 win over the Steelers, the Colts’ defense gave up 282 passing yards on 22 completions. They allowed one passing touchdown and held Pittsburgh to a 64.7% completion rate. Despite their success in getting to the quarterback (4 sacks), the Colts allowed the Steelers to convert on 46.2% of their third downs.

Indianapolis struggled more against the run, allowing 122 yards on 30 attempts. The Colts’ defense forced a lot of pressure, coming away with four sacks and leading in both tackles for loss and QB hit differentials.

In their most recent game, the Jaguars’ defense gave up 27 completions to the Texans for 334 yards through the air, including two passing touchdowns. They allowed Houston to convert on 53.8% of their third down attempts and hit on 67.5% of their passes. Overall, the Jaguars allowed 435 total yards in their 24-20 loss to the Texans.

Jacksonville did manage to come up with two sacks and had a positive differential in quarterback hits and tackles for loss. On the ground, the Jaguars gave up 101 rushing yards on 26 attempts.

  • Free MoneyLine Prediction UNDER 46 (Bet Now)

Colts vs. Jaguars Prediction: Spread

The Colts’ 27-24 win over the Steelers brought their record to 2-2 for the season. Despite falling behind 14-0 early, Indianapolis fought back to take a 27-24 victory. The Colts led 17-3 at halftime and even though the Steelers closed the gap in the 3rd quarter, Indianapolis still came out on top.

Indianapolis was +2.5 point underdogs heading into the game, and their 3-point win also resulted in a win against the spread. The combined 51 points easily surpassed the over/under line of 41 points. The Colts’ strong start saw them leading 14-0 after the 1st quarter, and although the Steelers fought back, Indianapolis still came out on top.

  • Over their last three games, the Colts have gone 2-1 straight up. This also includes going 2-1 ATS and an over-under mark of 1-2.
  • In their last five games away from home, the Colts have a straight up record of 2-3 while going 2-3 vs. the spread. The team averaged 15 points per game in this stretch.

Despite leading 20-17 heading into the 4th quarter, the Jaguars dropped their most recent game to the Texans, 24-20, bringing their record to 0-4. Jacksonville took an early 10-7 lead after Trevor Lawrence’s touchdown to Brian Thomas Jr. in the 1st quarter. The Jaguars added a late touchdown in the 3rd quarter to tie the game at 20, but the Texans outscored them 7-0 in the 4th quarter.

Jacksonville’s Christian Kirk also found the endzone in the 3rd quarter. The Jaguars missed a chance to win this one late, as with 0:22 remaining, C.J. Stroud connected with Nico Collins for a go-ahead touchdown for the Texans. The Jaguars were 5.5-point underdogs on the road, and their 24-20 loss was just short of a straight-up win.

  • Through their last three regular season contests, Jacksonville has a record of 1-2. Against the spread, Jacksonville went 1-2 in these games and finished with an over-under mark of 0-3.
  • In their last five games at home, the Jaguars have a straight up record of 0-5 while going 2-3 vs the spread. The team’s offense averaged 15 points per game in these contests.
  • Free Spread Prediction Colts +3 (Bet Now)

Colts vs. Jaguars Pick: Colts Moneyline (+127)

For this week five matchup between the Colts and Jaguars, we have the Colts coming out on top by a score of 24-21. With the Jaguars being the home team, they are currently sitting as 3-point favorites. However, our pick vs. the spread is to take the Colts to cover as road underdogs.

As for the over/under, with the line sitting at 46 points, we are leaning towards taking the under with a projected combined score of 45 points.

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