Lutz’s Locks For Week 4 Of The NFL

49ers vs Rams Prediction & NFL Odds For Week 3

ByUSA Wager

The 49ers are favored on the road with a money line of -349 as they take on the Rams at 4:25 ET on Sunday, September 22nd. The Rams are the +276 money line underdogs in this one, which is being televised by FOX. The 49ers are -7 point favorites and the over/under line is set at 43.5 points. The game is being played at SoFi Stadium in Inglewood, CA.

Prediction at a Glance for Rams vs 49ers

  • We have the Rams winning this one by a score of 19 to 17
  • Not only do we have the Rams winning straight-up, we have them covering the spread at +7
  • We see this game finishing below the line of 43.5 points

Betting Odds & Lines for this Game

  • Spread: 49ers -7 | Rams +7
  • Total: 43.5
  • MoneyLine: 49ers -349 | Rams +276

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

49ers vs. Rams Prediction: MoneyLine

In their 23-17 loss to the Vikings, the 49ers’ offense picked up 24 first downs and 297 yards through the air. They struggled on third down, converting only 20% of their chances, and their quarterback, Brock Purdy, was sacked six times. Purdy completed 77.8% of his passes for 319 yards, with one touchdown and one interception.

Jordan Mason led the ground game with 100 yards on 20 carries, including a long run of 22 yards and one touchdown. Deebo Samuel Sr. was the top receiver, finishing with 110 yards on eight catches.

The Rams’ offense struggled to move the ball in their 41-10 loss to the Cardinals, managing only 14 first downs and 192 yards passing. They were held to just 53 yards on 20 attempts. Los Angeles also allowed five sacks and converted only 18.2% of their third down attempts.

Matthew Stafford completed 70% of his passes for 216 yards, but failed to get into the endzone. Blake Corum was their leading rusher with 28 yards, while Demarcus Robinson led the team in receiving with 50 yards.

  • Free MoneyLine Prediction Rams +276 (Bet Now)

49ers vs. Rams Prediction: Total

Despite forcing four sacks and one interception, the 49ers’ defense struggled on third downs in their 23-17 loss to the Vikings, allowing a 58.3% conversion rate. They gave up 146 rushing yards on just 24 attempts, with Minnesota finding a lot of success on the ground, averaging 6.1 yards per attempt. Overall, the 49ers allowed 403 total yards and 9.9 yards per pass attempt.

Offensively, the 49ers had 146 rushing yards on 27 attempts, and Jimmy Garoppolo completed 16 of 33 passes for 168 yards and one touchdown. The defense will be looking to improve their performance on third downs and against the run in their next game.

In their 41-10 loss to the Cardinals, the Rams’ defense struggled to stop the run, giving up 231 yards on 40 attempts. Arizona’s big-play ability was on full display, as they averaged 5.8 yards per attempt. The Rams also struggled against the pass, allowing three passing touchdowns and giving up 258 yards through the air on just 17 completions.

Los Angeles’ defense had a tough time getting off the field, as the Cardinals converted on 63.6% of their third down attempts. The Rams managed only one sack and were outplayed in the trenches, losing the tackles for loss battle by a margin of -6.

  • Free MoneyLine Prediction UNDER 43.5 (Bet Now)

49ers vs. Rams Prediction: Spread

The 49ers are now 1-1 after a 23-17 loss to the Vikings. San Francisco was on the road for this one and despite being favored by -4, they lost straight-up and against the spread. The game finished with a combined total of 40 points, falling short of the over/under line of 46.5 points. The 49ers fell behind early, trailing 3-0 after the 1st quarter and 13-7 at halftime.

The Vikings extended their lead to 20-7 in the 3rd quarter before the 49ers made things interesting with a touchdown to George Kittle early in the 4th quarter, making it a 20-14 game. However, Minnesota responded with a touchdown and put the game out of reach at 37-14. Despite one last touchdown from San Francisco and a Jordan Mason rushing touchdown, the 49ers fell by 13.

  • Through their last three regular season contests, San Francisco has a record of 1-2. The team’s record vs the spread was just 1-2, in addition to an over-under mark of 1-1-1.
  • In their last five road games, San Francisco has averaged 30 points per game while allowing 21 . The team’s record in this stretch was 3-2 while going 3-2 vs. the spread.

It was a tough start for the Rams in their most recent game, falling behind 14-0 to the Cardinals after the 1st quarter. Things didn’t get any better from there, as they lost 41-10, dropping their record to 0-2. The Rams were forced to play from behind the entire game, and by halftime, they were down 24-3. The 41 points allowed was the most in the NFC West matchup.

Even though they found the endzone in the 3rd quarter, the game was already out of reach, with the Cardinals leading 34-10 heading into the 4th. The Rams didn’t help their cause by not even coming close to covering the spread, losing by 31 points. The over/under line heading into the game was 47.5 points.

  • Through their last three games, the Rams have a record of 3-0. In these games, they have a 3-0 record vs the spread and an over-under mark of 2-1.
  • In their last five games at home, the Rams have a straight up record of 2-3 while going 2-3 vs. the spread. The team averaged 20 points per game in this stretch.
  • Free Spread Prediction Rams +7 (Bet Now)

49ers vs. Rams Pick: Rams Moneyline (+276)

Our pick vs. the spread is to take the 49ers to cover, as the Rams are currently 7-point favorites. This line is a bit too high for our liking, as we have the Rams winning 24-16, but the 49ers covering as road underdogs.

For the over/under, we have a slight lean towards the under, with a projected combined score of 40 points and the line sitting at 43.5 points.

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