Mariners vs Astros Prediction & MLB Odds For Wednesday, September 25th

The money line odds for Wednesday’s Mariners vs. Astros game have the Mariners favored at -134 compared to the Astros at +113. The over/under line is currently at 7 runs, and the game is being played at 2:10 PM ET at Minute Maid Park in Houston. George Kirby is starting for the Mariners, and he is facing off against Yusei Kikuchi for the Astros.

The Astros are currently 1st in the AL West with a record of 86-72, while the Mariners are 2nd in the division at 81-77. Looking at the run line odds, the Mariners are +129 compared to the Astros at -158. Seattle is 5-5 over their last 10 games, while the Astros have gone 6-4.

Betting Odds & Lines for this Game

• Spread: Mariners -1.5 (+129) | Astros 1.5 (-158)
• Total: 7
• MoneyLine: Mariners -134 | Astros +113

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Mariners vs. Astros Prediction: Moneyline

Houston picked up a 4-3 win over the Mariners in the most recent game of this series. The Astros had a three-run 5th inning and scored the game’s go-ahead run in the 6th. As for the Mariners, they scored two runs in the 1st and added their final run in the 5th.

Seattle wasted a good outing from Logan Gilbert, as he gave up just three earned runs in six innings of work. As for the Astros, Framber Valdez gave up three earned runs in 5 2/3 innings of work. He did pick up the win in the game.

Jorge Polanco went 4/4 with a home run, but it came in a losing effort. Alex Bregman and Jason Heyward each homered for the Astros’ offense.

Seattle is on the road today, taking on the Astros in the second game of their series. The Mariners are 81-77 overall, putting them five games behind the Astros in the AL West. So far, they have gone 28-20 against other teams in the AL West.

The Mariners have been good at home this year, going 46-32, but they are just 35-45 on the road. So far, they have been slightly better as the favorite, where they are 58-48. As the underdog, the Mariners are 23-29 this year. Seattle’s overall series record is 21-24-4, and they have won two straight series on the road.

Houston currently leads the AL West by five games over the Mariners. The Astros are 86-72 overall and have gone 29-22 against other teams in the division. So far, they have been good at home, going 46-34, and they are just above .500 on the road at 40-38.

The Astros have an overall series record of 27-20-2, and they are 19-21 as the underdog this season. As for their overall record, they are 67-51 when favored. Houston is 6-4 across their last ten games and are coming off a win over the Mariners in their most recent game.

Mariners vs. Astros Prediction: Over/Under

Seattle’s over/under record is 74-74, and the average over/under line for their games is 8. Today’s over/under line is set at 7, and the Mariners have played 100 games with lines set higher than 7, which accounts for 63.3% of their games. Their combined run average is 7.9 runs per game, and their over/under record when the line is set at 7 runs is 17-20-8. They have played 13 games with lines set lower than 7 runs, which is just 8.2% of their games.

Julio Rodríguez has been on fire for the Mariners as of late, going 17/40 in his last eight games with three homers and 11 RBIs. For the season, he is batting .275 with 19 homers, which is 4th on the team. Catcher Cal Raleigh is 15th in the league with 96 RBIs and has gone deep 31 times this season. However, he is batting just .218.

As a team, the Mariners are batting just .224, which is 22nd in the league, and are averaging 4.1 runs per game. This is the 11th best home run-hitting team in the league, and they have been good at drawing walks. Overall, they are the worst team in the league in terms of strikeouts.

The Houston Astros have played 152 games this season, and only one of them has had an over/under line set at 7 runs. Their combined run average for the season is 8.6 runs per game, and their over/under record is 64-88. The average over/under line for their games this season is 8 runs, and 95.6% of their games have had lines set higher than 7 runs.

Yordan Alvarez has been a huge power threat for the Astros this season, as his 35 home runs are the best mark on the team and 8th best in the league. He also leads the team with 86 RBIs and comes into the game with a strong batting average of .308. Alex Bregman has also been swinging the bat well of late, going 7/20 with three homers over his last five games.

As a team, the Astros are averaging 4.6 runs per game and are one of the league’s top offensive clubs in terms of batting average, on-base percentage, and slugging percentage. They have been even better at home, averaging 4.9 runs per contest.

Mariners vs. Astros Prediction: Spread

Seattle is 69-89 on the run line this season, including a 36-44 mark on the road. The Mariners have been a better bet at home, where they are 33-45 against the run line. Their average run differential is +0.4 runs per game, but they have been outscored by an average of 3.1 runs in their losses.

Seattle is sending right-hander George Kirby to the mound today vs. the Astros. He has made 32 starts this year and has a record of 13-11 with a 3.60 ERA. Kirby’s WHIP for the season is currently 1.08. In his 32 appearances, he has turned in 19 quality starts and is averaging 8.42 strikeouts per nine innings. Looking back at his most recent outing, Kirby picked up the win vs. the Rangers, going six innings and giving up two earned runs on five hits. Before that, he had won two straight starts. So far, he has been much better at home, coming in with a 4.47 ERA on the road compared to 3.8 at home.

When the Astros win, they win big, with an average run margin of 3.7 runs per game. That’s helped them to a run line record of 81-77 on the season. They’ve been a better bet on the road, where they are 43-35 against the run line, compared to 38-42 at home. They’ve been a good bet as the underdog, going 26-14 against the run line, compared to 55-63 as the favorite.

Left-hander Yusei Kikuchi gets the start for the Astros today as he faces off against the Mariners. He has made 31 starts this season and has a record of 9-9 with an ERA of 4.19. Kikuchi’s WHIP for the season is 1.21, and he has turned in 11 quality starts. Kikuchi’s most recent outing came against the Angels, where he finished with a no-decision, going six innings and giving up one earned run on five hits. He did give up a homer in that outing. Before that, he had won three straight starts.

Mariners vs. Astros Pick: Astros ML +113

Our predicted score for this game is a 6-5 win for the Astros, and with them being the underdogs on the money line at +113, this is the way we recommend playing this one. If you’re looking for a parlay, you could also look to pair the Astros with the over, as the line is sitting at seven runs.

Looking at the starting pitchers, Yusei Kikuchi is projected to finish with six strikeouts compared to George Kirby at five. Kikuchi is also predicted to finish with fewer hits allowed than Kirby, and if you’re looking for a player prop bet, Kikuchi’s strikeout line could be a good option.