Diamondbacks vs Astros Prediction & MLB Odds For Saturday, September 7th

At 4:10 PM ET, the Diamondbacks and Astros square off in an interleague matchup. This one is being played at Minute Maid Park in Houston and has the Astros as heavy favorites on the money line (-165). The Diamondbacks are +141 on the money line, and their over/under line is currently at 8 runs.

Arizona comes in with a record of 79-63 and will be looking to end a two-game losing streak. They are 3rd in the NL West, while the Astros are 1st in the AL West, as they are 76-65.

Betting Odds & Lines for this Game

• Spread: Diamondbacks 1.5 (-153) | Astros -1.5 (+127)
• Total: 8
• MoneyLine: Diamondbacks +141 | Astros -165

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Diamondbacks vs. Astros Prediction: Moneyline

Houston cruised to an easy 8-0 win over the Diamondbacks in the most recent game of this series. The Astros had a huge 2nd inning, scoring seven of their eight runs. As for the Diamondbacks, they had their best chance to score in the 5th, but left the bases loaded.

Framber Valdez pitched well for the Astros in this one, going seven innings and striking out seven without giving up a run. He picked up a win in the game, while Brandon Pfaadt took the loss for Arizona. Pfaadt only went 4 2/3 innings and gave up four earned runs.

Yordan Alvarez hit the game’s only two home runs while going 2/4 with six RBIs. Jose Altuve also had a three-hit game and scored twice for Houston’s offense.

Arizona is 79-63 overall this season, and they trail the Dodgers by 5.5 games in the NL West. The Diamondbacks have dropped two straight games, and they are 3rd in the division. So far, they have gone 25-18 in divisional games.

At home, the Diamondbacks are 39-31 this year, and they are above .500 at 40-32 on the road. Arizona has dropped five straight games as the underdog, and they are 34-37 as the underdog overall. As the favorite, the Diamondbacks are 45-26 this year, and their overall series record is 25-16-4. Arizona has won three straight series on the road and has dropped two straight at home.

The Astros are 76-65 overall this season, and they lead the AL West by 4.5 games over the Mariners. Currently, they are 21-18 in divisional matchups. Houston has been tough to beat at home, going 40-29 this year, and they are an even 36-36 on the road.

So far, the Astros have been good as the favorite, putting together a mark of 58-46. As the underdog, Houston is 18-19 this season. They come into today’s game having won five straight at home, and their overall series record is 24-19-2.

Diamondbacks vs. Astros Prediction: Over/Under

The Diamondbacks are on the road in Houston today, and the over/under line for the game is set at 8 runs. Arizona’s games have averaged 10.2 runs per game this season, and their over/under record is 81-54. When the over/under line has been set at 8 runs this season, the over has hit in 10 games, the under in 5, and there have been 2 pushes. Overall, 70.4% of their games have had higher over/under lines than 8 runs.

Arizona comes into the game as the top-scoring team in the league, averaging 5.4 runs per contest. They have been even better at home, putting up 5.6 runs per game. Not only do the Diamondbacks lead the league in on-base percentage, but they are also the top team in terms of slugging. As a team, they are batting .261, which is the 2nd best mark in the league.

Ketel Marte has been the team’s top power threat this season, as his 30 homers is the best mark on the team and 12th best in the league. He is also 2nd on the team with 81 RBIs. Marte’s batting average of .296 is the best mark on the team, and he has been red hot of late, going 6/17 with two homers over his last five games. Eugenio Suarez has also gone deep 24 times this season and is coming off a stretch in which he hit .353.

When the Astros play at home, the over/under line is set at 8 runs, which is lower than their season average of 9 runs per game. Their over/under record for the season is 56-80, and when the line is set at 8 runs, their record is 11-13-2. Overall, 60.3% of their games have had higher lines than 8 runs.

Yordan Alvarez has been the Astros’ top hitter this season, as he is batting .310 with 32 homers and 79 RBIs. Over his last five games, Alvarez has four homers and eight RBIs while going 5/19. Alex Bregman is also a big power threat for the Astros, as he has 21 homers and 61 RBIs this season but is batting just .259.

As a team, the Astros are 3rd in the league in batting average and are averaging 4.6 runs per game. They are also one of the top home run-hitting teams in the league and are averaging 4.8 runs per game at home. Overall, they are 10th in the league in scoring.

Diamondbacks vs. Astros Prediction: Spread

Arizona has a run differential of +0.6 runs per game this season, and their run line record is 74-68. They are 42-30 against the run line on the road, where they have a run differential of +0.6 runs per game. As the underdog, they are 44-27 against the run line, and their average run differential in wins is +4.1 runs per game.

Eduardo Rodriguez and the Diamondbacks are on the road to take on the Astros. He has started 3 games this season, and his last start was a loss to the Dodgers, where he went 4 innings and gave up 3 runs. Rodriguez has 11 strikeouts in 14 2/3 innings this season.

The Astros have covered the run line in three straight games and are 33-36 at home this season. Houston’s average run margin in winning games is 3.8, while its average run margin in losing games is -3.1. The Astros are 72-69 against the run line overall and 39-33 on the road.

Left-hander Yusei Kikuchi gets the start for the Astros today as he faces the Diamondbacks at home. He has made 28 starts this season and has a record of 7-9 with an ERA of 4.24. Kikuchi’s WHIP for the season is 1.25. In his last outing, Kikuchi picked up the win, going seven innings and giving up just one earned run on five hits. Looking back further, he has allowed just one earned run in three of his last four outings. Kikuchi has a total of nine quality starts this season and is averaging 10.57 strikeouts per nine innings.

Diamondbacks vs. Astros Pick: Over 8 Runs -119

Our predicted final score for this game is 6-5 in favor of the Astros, which would make a money line bet on the Astros a good option. However, with the payout being -165, we recommend taking the over, as there is some good value there.

Looking at some of the starting pitcher projections, Eduardo Rodriguez is predicted to finish with six strikeouts, compared to Yusei Kikuchi with seven. If you’re looking for a player prop bet, you could take Kikuchi’s over on his strikeout line.