Astros vs Reds Prediction & MLB Odds For Wednesday, September 4th

Wednesday’s interleague matchup between the Astros and Reds has a first pitch set for 6:40 PM from Great American Ball Park in Cincinnati. The Reds are currently on a two-game winning streak and are 66-73 overall, while the Astros, who are 1st in the AL West, have a record of 75-63.

Spencer Arrighetti is starting for the Astros, and he will be facing off against Nick Martinez for the Reds. Houston is the favorite on the money line, and the over/under line is currently at 9 runs. BSOH is carrying this one on TV.

Betting Odds & Lines for this Game

• Spread: Astros -1.5 (+111) | Reds 1.5 (-134)
• Total: 9
• MoneyLine: Astros -141 | Reds +120

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Astros vs. Reds Prediction: Moneyline

Cincinnati picked up a 5-3 win over the Astros in the most recent game of this series. The Reds had a huge 5th inning, scoring all five of their runs. As for the Astros, they scored one run in the 7th and added their final two runs in the 8th. Heading into the game, the Reds were at +137 on the money line.

Justin Verlander got the start for the Astros, going just 4 2/3 innings while giving up five runs and took the loss. Julian Aguiar only went 2 2/3 innings for the Reds but gave up just two hits and two earned runs. He did not factor in the decision.

Ty France was the only player in the game to have more than two hits, as he went 4/4 with an RBI. Yainer Diaz had a three RBI game for the Astros, going 2/3.

The Astros are 75-63 overall this season, and they lead the AL West by 6.5 games over the Mariners. So far, they have gone 21-18 in divisional matchups. Houston will take on the Reds today on the road, and they are 36-34 on the road this year.

So far, the Astros have been good as the favorite, putting up a record of 57-44. As the underdog, they are 18-19 this season. Houston’s overall series record is 24-18-2, and they are currently down 0-1 in this series vs. the Reds.

Cincinnati is 66-73 overall, putting them 4th in the NL Central. Currently, they trail the Brewers by 15 games in the division. The Reds are 20-23 in divisional games this season. They have won two straight games, and their series lead over the Astros is 1-0.

At home, the Reds are 34-39 this season, while going 32-34 on the road. So far, they have been an even 33-33 as the favorite and 33-40 as the underdog. Cincinnati’s overall series record is 16-25-3, and they have dropped three straight series.

Astros vs. Reds Prediction: Over/Under

When the Astros are on the road, the over/under line is set at 9 runs. Their games have averaged 8.5 runs per game this season, and their over/under record is 54-79 overall. When the line is set at 9 runs, their over/under record is 11-8-2. So far this season, 19 of their games have had over/under lines set at 9 runs, accounting for 13.8% of their games.

Yordan Alvarez has been on a tear for the Astros, not only leading the team with 30 homers but also batting .313 for the season. Over his last six games, Alvarez has gone 11/23 with five homers and six RBIs. Alex Bregman is 2nd on the team with 21 homers but is batting just .260 this season.

As a team, the Astros are 3rd in the league with a batting average of .260 and are also among the league leaders in runs scored. Overall, they are averaging 4.6 runs per game and have been even better at home, averaging 4.7 runs per contest.

The Reds have played to the over in 65 of their 132 games this season, but their games have averaged just 8.8 runs per game. When the O/U line is set at 9 runs, the under has gone 19-5-5 in their games. The under has hit in two straight games for Cincinnati.

Elly De La Cruz has been a key power bat for the Reds this season, as he is 15th in the league with 22 home runs, while also batting .261. His 61 RBIs are 2nd on the team. Leading the Reds in RBIs is Spencer Steer, who has 85 RBIs this season, which is 15th in the league. Steer is also 3rd on the team with 19 homers, but he has struggled with a batting average of just .234.

Jonathan India has been swinging a hot bat of late, going 6/18 in his last five games with a home run and four RBIs. Amed Rosario has also been swinging it well, going 4/14 in his last five games, including a home run. Rosario comes into the game on a three-game hitting streak.

Astros vs. Reds Prediction: Spread

When the Astros win, they win big, with an average run margin of 3.7. Their run line record is 71-67, and they are 32-36 against the run line at home. As the underdog, they are 25-12 against the run line, and their overall run line record is 39-31 on the road.

Houston is sending right-hander Spencer Arrighetti to the mound today as he faces the Reds on the road. Arrighetti has made 24 starts this season and has a record of 7-11 with a 4.63 ERA. In his 24 appearances, he has turned in eight quality starts and is averaging 10.93 strikeouts per nine innings. Arrighetti’s WHIP for the season is 1.38. In his most recent outing, he pitched 7 2/3 innings, picking up the win and not allowing a run. Before that, he had won two straight starts. Opponents are batting .232 off Arrighetti this season.

The Reds have been a solid run-line bet this season, going 74-65 overall. They have been even better on the road, going 41-25 against the run line. They have been an underdog in 73 games and have gone 47-26 against the run line in those contests. Their average run differential in wins is +3.8, while it is -3.2 in losses.

Right-hander Nick Martinez gets the start for the Reds today as he faces the Astros at home. He has made 11 starts this season and has a record of 6-6 with an ERA of 3.77. Martinez has made 37 appearances this year and is coming off a start in which he finished with a no-decision. In that outing against the Brewers, he went 5 1/3 innings, giving up four earned runs, and one homer. Looking back at his last three outings, Martinez has finished with a no-decision in each one. He has made two quality starts this year and is averaging 7.06 strikeouts per nine innings.

Astros vs. Reds Pick: Reds ML +120

Our prediction for this Astros vs. Reds matchup is to take the Reds on the money line, with a payout of +120. We have the Reds winning this one by a final score of 6-5.

Looking at the starting pitchers, we have Nick Martinez finishing with seven strikeouts compared to Spencer Arrighetti, who is projected to finish with seven as well. However, we have Martinez finishing with a better ERA and picking up the win, with Arrighetti’s chances of getting a win ranking 10th among starters.