Angels vs Astros Prediction & MLB Odds For Saturday, September 21st

First pitch for Saturday’s matchup between the Angels and Astros is set for 7:10 PM ET from Minute Maid Park in Houston. The Astros are currently 1st in the AL West with a record of 84-70, while the Angels are 5th in the division at 62-92. Houston is the heavy favorite on the money line, with their odds sitting at -244, while the Angels are at +204.

The over/under line is currently at 8 runs, and the Astros will be looking to extend their winning streak to three games, while the Angels are on a two-game losing skid. Reid Detmers is starting for the Angels, and he is facing off against Ronel Blanco.

Betting Odds & Lines for this Game

• Spread: Angels 1.5 (-109) | Astros -1.5 (-112)
• Total: 8
• MoneyLine: Angels +204 | Astros -244

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Angels vs. Astros Prediction: Moneyline

Houston picked up a 9-7 win over the Angels in the most recent game of this series. The Astros had a huge 3rd inning, scoring five of their nine runs. As for the Angels, they scored three of their seven runs in the 4th. Heading into the game, the Astros were favored at -251 on the money line.

Justin Verlander got the start for the Astros, going just 4 2/3 innings while giving up six runs and striking out four. He did pick up a win in the game. Hector Neris got the save. Tyler Anderson had a rough outing for the Angels, taking the loss after going just 2 2/3 innings and giving up three earned runs.

Kyle Tucker was the difference for the Astros, as he went 4/5 with a home run and three RBIs. Alex Bregman and Jake Meyers each drove in three for Houston’s offense.

With a record of 62-92, the Angels are 5th in the AL West and trail the Astros by 22 games for the division lead. So far, they have gone 20-27 in AL West matchups. The Angels have dropped two straight games and are just 2-8 over their last 10 games.

At home, the Angels are 32-46 this year, and they are just one game under .500 at 30-41 on the road. This season, the Angels have really struggled as the underdog, as their record is 54-76. Their losing streak as the underdog is at seven games, and they are 8-16 as the favorite this year. The Angels’ overall series record is 13-32-3.

Houston is currently 84-70 overall and leads the AL West by five games over the Mariners. The Astros have won two straight games, and this comes after taking two of three from the Angels. So far, they have gone 27-20 in divisional games this year.

At home, the Astros are 44-32 this year and have gone 40-38 on the road. Houston has won three straight games at home, and they are 41-27 as the home favorite this year. As the underdog, the Astros are 19-21 this season.

Angels vs. Astros Prediction: Over/Under

The Angels are on the road against the Astros today, and the over/under line is set at 8 runs. The combined run average for Angels games this season is 8.8 runs, and their over/under record is 73-75. When the over/under line is set at 8 runs, their record is 18-10-2. Overall, 70.8% of their games this season have had over/under lines set higher than 8 runs.

So far this season, the Angels are averaging just 3.9 runs per game, which is the worst mark in the league. They are also near the bottom of the league in most offensive categories, including team batting average, on-base percentage, and slugging percentage. As a team, the Angels are batting just .229, and their on-base percentage of .301 is also one of the worst in the league.

Both Taylor Ward and Zach Neto are batting .247 for the season, with Ward leading the team with 25 homers and 71 RBIs. Ward and Neto have also both gone deep twice in their past seven games. Eric Wagaman has also been swinging a hot bat of late, going 11/31 in his last seven games with two homers.

The Houston Astros will be playing the Los Angeles Angels at home today, with the over/under line set at 8 runs. The combined run average in Astros games this season is 8.6 runs, and their over/under record is 62-87. The average over/under line in their games is 9 runs, and their over/under record when the line is set at 8 runs is 14-14-2. So far this season, 59.1% of their games have had over/under lines set higher than 8 runs.

The Astros come into today’s game as one of the league’s top offenses, averaging 4.6 runs per game (13th) and batting a collective .261, which is the 3rd best mark in the MLB. Houston has been very good at avoiding strikeouts this season, as they have the 3rd fewest strikeouts in the league. However, they are just 26th in the league in walks. At home, the Astros are averaging 4.9 runs per game, which is the 6th best mark in the league.

Yordan Alvarez has been the Astros’ top power hitter this season, as his 34 homers are the best on the team and 9th best in the league. He also leads the team with 85 RBIs. Jose Altuve and Alex Bregman are also near the top of the team’s home run and RBI leaderboards. Altuve is batting .297 for the season, while Bregman comes in at .255.

Angels vs. Astros Prediction: Spread

When the Angels are favored, they are 6-18 on the run line. When they are the underdog, they are 70-60 on the run line. Their average run differential in winning games is +3.1 runs, while it is -3.6 runs in losing games. Overall, they are 76-78 on the run line this season.

Left-hander Reid Detmers gets the start for the Angels today as he faces the Astros on the road. He has made 15 starts this season and has a record of 4-7 with a 6.05 ERA. Detmers’ WHIP for the season is 1.43, and opponents are batting .248 off him this year. In his 15 appearances, Detmers has turned in four quality starts. Looking back at his most recent outing, he took the loss vs. the White Sox, giving up seven earned runs in 5 1/3 innings of work. Before that, he had won two straight starts.

When the Astros are at home, they have been a solid bet on the run line, going 37-39. Their average run differential in home games is +1.1 runs per game. They have covered the run line in three straight home games and are 54-60 on the run line as the favorite this season.

Ronel Blanco gets the start for the Astros today and has been pitching well as of late. In his 27 starts, he has a record of 11-6 and an ERA of 2.88. Blanco’s WHIP for the season is 1.09, and he has one complete game shutout to go along with 13 quality starts. Blanco’s most recent outing came against the Angels, where he picked up the win, going six innings and not giving up a run. He only allowed five hits and two walks in that outing. Blanco has made 15 starts at home, going 5-4 with a 3.51 ERA.

Angels vs. Astros Pick: Over 8 Runs -113

Our prediction for the Astros vs. Angels matchup is to take the over, as we see this one finishing with a score of 5-4 in favor of the Astros. With the over/under sitting at 8 runs, there is a little bit of wiggle room, but we would still take the over, even with the payout sitting at -113.

Looking at the starting pitchers, we have Ronel Blanco finishing with six strikeouts compared to Reid Detmers with five. Blanco is also projected to go 5.2 innings compared to Detmers at 4.2.

Another reason we like the over is that the Angels are projected to finish with just four runs, and their offense is projected to finish with the second-fewest hits in the league today.