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Patriots vs Cardinals Prediction & NFL Odds For Week 15

ByUSA Wager

The Patriots and Cardinals will face off on Sunday, December 15th at 4:25 ET on CBS. The Patriots are the road underdog with a point spread of +6 and money line odds of +220. The Cardinals are favored with money line odds of -269. This week 15 non-conference matchup is being played at State Farm Stadium in Glendale, AZ, and the over/under line is set at 45.5 points.

Prediction at a Glance for Cardinals vs Patriots

  • We have the Patriots winning this one by a score of 26 to 24
  • Not only do we have the Patriots winning straight-up, we have them covering the spread at +6
  • Look for this game to go over the line of 45.5 points

Betting Odds & Lines for this Game

  • Spread: Patriots +6 | Cardinals -6
  • Total: 45.5
  • MoneyLine: Patriots +220 | Cardinals -269

All Odds are courtesy of (BetMGM | DraftKings | Fanduel | BetRivers)

Patriots vs. Cardinals Prediction: MoneyLine

Heading into week 15, the Patriots rank 27th in our offensive power rankings. They are 29th in the NFL in points per game (17) and 31st in passing yards per game (171.5), despite ranking 16th in pass attempts. On the ground, they average 119.5 rushing yards per game, ranking 13th in the league, on 26.3 attempts per game. New England ranks 23rd in 3rd-down conversions, with a 35.4% success rate, but they have been efficient in the red zone, converting 47.4% of their trips, which ranks 8th in the NFL.

Drake Maye has posted solid numbers over his last three games, including a 24/30 performance for 238 yards and a touchdown in week 13. He had a passer rating of 74 in week 12 and threw for 282 yards and 2 touchdowns in week 11. Rhamondre Stevenson led the Patriots with 73 rushing yards on 18 carries in week 13, while Hunter Henry had 7 receptions for 75 yards.

Heading into week 15, the Cardinals rank 14th in our offensive power rankings. They are 16th in the NFL in points per game, averaging 21.8, and 12th in yards per game with 348. Arizona ranks 21st in passing attempts and passing yards per game, averaging 208.2. On the ground, they are 12th in rushing attempts and 6th in rushing yards per game, with 139.8. The Cardinals have been strong on 3rd down, converting 40.4% of their attempts, which ranks 10th in the league.

Kyler Murray threw for 259 yards in week 14, completing 25 of 38 passes with 2 touchdowns and 2 interceptions. James Conner rushed for 90 yards on 18 carries, while Trey McBride led the team in receiving with 7 catches for 70 yards. Arizona scored 7 points in the 1st quarter but failed to score in the 4th quarter against Seattle.

  • Free MoneyLine Prediction Patriots +220 (Bet Now)

Patriots vs. Cardinals Prediction: Total

Despite giving up 144 rushing yards, the Patriots’ defense held the Colts to just 109 yards passing on 12 completions in their most recent game. New England’s defense also forced two interceptions and limited the Colts to 25 points in a 25-24 loss. The Patriots defended the run with some success, as Indianapolis ran the ball 34 times.

However, New England’s defense struggled on third downs, allowing the Colts to convert 45.5% of their chances. The Patriots didn’t record any sacks in the game and gave up two passing touchdowns. Even though the Patriots’ offense turned the ball over three times, their defense kept them in the game by allowing just 253 total yards.

In their 30-18 loss to the Seahawks, the Cardinals gave up 176 rushing yards on 31 attempts. Overall, the Arizona defense allowed 409 yards, with Seattle finding success in the running game, averaging 5.7 yards per attempt. The Cardinals struggled to pressure the quarterback, failing to record any sacks and losing the QB hit and tackles for loss differentials.

In the passing game, Arizona allowed 80% of Seattle’s passes to be completed for 233 yards. On third downs, the Seahawks converted 46.7% of their chances, contributing to their 30 points in the game.

  • Free Total Prediction OVER 45.5 (Bet Now)

Patriots vs. Cardinals Prediction: Spread

Heading into week 15, the Patriots are on a three-game losing streak, dropping their record to 3-10. New England ranks 27th in our NFL power rankings and has no chance of making the playoffs. They are 4th in the AFC East with a 1-3 division record and are 2-7 in conference play. The Patriots are 1-5 at home and 2-5 on the road this season.

New England is 5-7-1 against the spread, having been the underdog in all of their games. Their average scoring margin is -6.6 points per game. The over has hit in three straight Patriots games, bringing their O/U record to 8-5 this season.

  • Through their last three regular season contests, New England has a record of 0-3. This includes going 1-2 vs. the spread along with an over-under mark of 3-0.
  • Across their five previous road games, New England has an ATS mark of 2-3. Their straight up record in these matchups was 1-4 while averaging 16 points per game.

Arizona heads into week 15 against the Patriots looking to snap a three-game losing streak, which includes a 30-18 home loss to the Seahawks in week 14. The Cardinals were 3-point favorites in that game but couldn’t get the win, dropping their record to 6-7. They now sit 3rd in the NFC West with a 2-2 division record and are 10th in the conference standings.

According to our projections, Arizona has an 8.5% chance of making the playoffs and a 7.3% chance of winning the division. They are 15th in our NFL power rankings. The Cardinals have an average scoring margin of -0.4 points per game and are 8-5 against the spread this season. They are 6-2 ATS as underdogs but just 1-3 as favorites.

  • Over their last three games, the Cardinals have gone 2-1 straight up. The team has also been excellent vs the spread, going 2-1. Their over-under record in these games was 1-2.
  • When looking at their past five home matchups, Arizona has an ATS record of 3-2 while averaging 18 per game. The team went 2-3 overall in these games.
  • Free Spread Prediction Patriots +6 (Bet Now)

Patriots vs. Cardinals Pick: Patriots Moneyline (+220)

Our pick vs. the spread is to take the Patriots to cover as road underdogs in this week 15 matchup between the Patriots and Cardinals. Right now, the point spread lines have the Patriots at +6, and we have them winning by a score of 30-21.

For the over/under, we really like the over, with a projected 51 combined points and the O/U line sitting at 45.5 points.

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